Table NPS / NPS or OPS carriage prevalences and the indirect VE of PhiD-CV10
Pathogen | N positives for NPS / NPS or OPS | Carriage percentage for NPS / NPS or OPS | VE for PHiD-CV10 groups combined | |||||
|---|---|---|---|---|---|---|---|---|
Control (N=509) | PHiD-CV10 2+1 (N=471) | PHiD-CV10 3+1 (N=433) | Control | PHiD-CV10 2+1 | PHiD-CV10 3+1 | Against NPS Estimate (95%CI) | Against NPS or OPS Estimate (95%CI) | |
Overall Pnc | 197 / 237 | 155 / 213 | 174 / 205 | 38 / 47 | 32 / 45 | 39 / 47 | 10 (−12, 28) | 2 (−22, 21) |
Vaccine-type Pnc | 100 / 125 | 69 / 90 | 65 / 79 | 19 / 25 | 14 / 19 | 14 / 18 | 29 (6, 47) | 29 (8, 46) |
H. influenzae | 71 / 96 | 63 / 79 | 54 / 74 | 14 / 19 | 13 / 17 | 12 / 17 | 9 (−25, 34) | 11 (−21, 35) |
S. aureus | 112 / 245 | 124 / 225 | 104 / 207 | 22 / 48 | 26 / 48 | 23 / 48 | −17 (−52, 9) | 2 (−23, 21) |
M. catarrhalis | 175 / 185 | 158 / 165 | 160 / 168 | 34 / 36 | 33 / 35 | 36 / 39 | −5 (−40, 20) | −5 (−41, 22) |