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Table 2 Cases and controls: demographics, recruitment, diagnosis, diagnostic specimens and follow up

From: Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

  Cases: n (%)(n = 998) Controls: n (%)(n = 978)
Demographics
 Median age (months; IQR) 7.8 months (3.9–14.3) 20.8 months (8.2–36.4)
 Male sex (%) 562 (56.3%) 520 (53.2%)
Recruitment year
 2013 286 (28.6%) 172 (17.6%)
 2014 291 (29.1%) 288 (29.4%)
 2015a 421 (42.2%) 518 (53.0%)
Recruitment site
 Children’s ward, EHPH 404 (40.5%) NA
 Outpatient clinics, EHPH 313 (31.4%)
 North Clinic 194 (19.4%)
 Lopi Clinic 7 (0.7%)
 PNGIMR Research Clinic 75 (7.5%)
 Unknown 5 (0.5%)
Diagnosis
 Moderate pneumonia
  • Without suspected meningitis
  • With suspected meningitis
784 (78.6%)
753
31
NA
 Severe pneumonia
  • Without suspected meningitis
  • With suspected meningitis
187 (18.7%)
170
17
 Suspected Meningitis (without pneumonia) 27 (2.7%)
Diagnostic specimens collected
 Blood culture 987 (98.9%) NA
 EDTA blood 512 (51.3%) NA
 Serum 363 (36.4%) NA
 CSF 31 (3.12%) NA
 Nasopharyngeal swab 998 (100%) 978 (100%)
 Urine 42 (4.2%) NA
Successful follow up (of eligible children) by year
 2013 156/223b (69.9%) NA
 2014 162/209b (77.5%)
 2015a 251/310b (81.0%)
  1. Abbreviations: IQR interquartile range, EHPH Eastern Highlands Provincial Hospital, NA not applicable
  2. a inclusive of the first 3 weeks of January 2016
  3. b denominator is children residing within 1 h by vehicle from Goroka