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Table 3 Antibiotic susceptibilities of Corynebacterium spp. identified as causes of pulmonary infection

From: Corynebacteria as a cause of pulmonary infection: a case series and literature review

 

Antibiotic

Organism

PCN

AMX

AMC

AMP

CEF

CFZ

CXM

CRO

CTX

SXT

ERY

AZM

CLI

CIP

C. accolens (n = 1)

100

 

100

     

100

0

0

 

0

 

C. afermentans (n = 1)

         

100

    

C. jeikeium (n = 5)

0

  

0

 

0

   

0

0

 

0

 

C. macginleyi (n = 1)

0

   

0

0

0

0

0

    

0

C. mucifaciens (n = 1)

100

100

     

100

      

C. propinquum (n = 1)

100

      

100

100

   

0

 

C. pseudodiphtheriticum (n = 24)

100

100

100

100

100

100

100

100

100

45

5

 

8

73

C. pseudotuberculosis (n = 2)

100

      

100

 

100

100

 

100

 

C. striatum (n = 7)

60

100

100

100

67

0

0

0

75

0

50

0

0

0

C. ulcerans (n = 2)

50

  

100

100

     

100

100

50

100

C. urealyticum (n = 1)

100

  

100

100

         

C. xerosis (n = 1)

0

 

0

0

0

 

0

  

0

0

  

0

Organism

LCM

RIF

GEN

TOB

VAN

LZD

IPM

AMK

DOX

TET

TEC

CHL

FOF

DAP

C. accolens (n = 1)

 

100

0

0

100

  

100

 

0

  

100

 

C. afermentans (n = 1)

    

100

 

100

       

C. jeikeium (n = 5)

 

100

50

 

100

  

100

   

50

  

C. macginleyi (n = 1)

    

100

         

C. mucifaciens (n = 1)

    

100

  

100

      

C. propinquum (n = 1)

    

100

 

100

      

100

C. pseudodiphtheriticum (n = 24)

0

75

100

100

100

 

100

100

100

100

86

27

  

C. pseudotuberculosis (n = 2)

 

100

    

100

  

100

    

C. striatum (n = 7)

100

60

100

100

100

100

80

50

 

50

100

   

C. ulcerans (n = 2)

 

100

100

 

100

 

100

  

100

 

100

  

C. urealyticum (n = 1)

         

100

    

C. xerosis (n = 1)

  

0

 

100

  

0

      
  1. Antibiotic susceptibility for each Corynebacterium spp. as reported in all previous cases of Corynebacterial pneumonia (see Table 1 for reference listing) was calculated from number of sensitive isolates as a percentage of the total number of isolates tested with that antibiotic. Blank boxes represent a lack of testing information. The total number of isolates of each species is provided (n). Not all isolates under each organism were tested for the same antibiotics.
  2. PCN penicillin, AMX amoxicillin, AMC amoxicillin-clavulanic acid, AMP ampicillin, CEF cefalothin, CFZ cefazolin, CXM cefuroxime, FOX cefoxitin, CRO ceftriaxone, CTX cefotaxime, OFX ofloxacin, SXT trimethoprim-sulfamethoxazole, ERY erythromycin, AZM azithromycin, CLI clindamycin, LCM lincomycin, RIF rifampin, GEN gentamicin, TOB tobramycin, VAN vancomycin, LZD linezolid, IPM Imipenem, AMK amikacin, DOX doxycycline, TET tetracycline, TEC teicoplanin, CHL chloramphenicol, FOF Fosfomycin, DAP daptomycin