| | 23vPPV in Pregnancy | | |
|---|
Yes (n = 75) | No (n = 150) | | |
|---|
Children, n (%) | Episodes, n | Child-years | IR | Children, n (%) | Episodes, n | Child-years | IR | HR (95%CI) | aHR (95%CI) |
|---|
ALRI hospital | 6 (8) | 9 | 73.1 | 12.3 | 19 (13) | 23 | 145.9 | 15.8 | 0.77 (0.29,2.03) | 0.92 (0.34,2.47) |
ALRI clinic# | 18 (78) | 45 | 20.9 | 215 | 34 (72) | 81 | 43.0 | 188 | 1.13 (0.67,1.93) | 1.24 (0.76,2.03) |
- ALRI acute lower respiratory infection, IR incidence rate per 100 child-years. HR hazard ratio, aHR adjusted hazard ratio, 95%CI 95% confidence interval. After stepwise elimination the covariates: remote dwelling, maternal smoking in pregnancy and breast feeding duration (time dependent) were included in the final ALRI hospital model; missing breast feeding duration data (n = 11) were imputed. After stepwise elimination the covariates: PCV doses (time dependent), breast feeding duration (time dependent) and maternal smoking during infancy were included in the final ALRI clinic presentation model. #ALRI clinic presentation data were only available for the 70 infants from remote communities (23vPPV n = 23; no 23vPPV n = 47); missing maternal smoking during infancy data (n = 7) were imputed
