From: E-cigarette, or vaping, product use-associated lung injury: a review
Case Classification | CDC Criteria | Additional investigations to consider: |
---|---|---|
Confirmed | Using an e-cigarette (“vaping”) or dabbingb during the 90 days before symptom onset (and) | Consider toxicology to assess for THC or other inhalational agents |
Pulmonary infiltrate, such as opacities on plain film chest radiograph or ground-glass opacities on chest computed tomography (and) | Consider CT scan for increased sensitivity | |
Absence of pulmonary infection on initial work-up: Minimum criteria include negative respiratory viral panel, influenza polymerase chain reaction or rapid test if local epidemiology supports testing. All other clinically indicated respiratory infectious disease testing (e.g., urine antigen for Streptococcus pneumoniae and Legionella, sputum culture if productive cough, bronchoalveolar lavage culture if done, blood culture, human immunodeficiency virus–related opportunistic respiratory infections if appropriate) must be negative (and) | HIV testing SARS-CoV-2 testing Procalcitonin CBC with differential | |
No evidence in medical record of alternative plausible diagnoses (e.g., cardiac, rheumatologic, or neoplastic process). | Echocardiography Differential on CBC ANA RF ANCA ESR CRP | |
Probable | Using an e-cigarette (“vaping”) or dabbingb in 90 days before symptom onset (and) | Consider toxicology to assess for THC or other inhalational agents |
Pulmonary infiltrate, such as opacities on plain film chest radiograph or ground-glass opacities on chest computed tomography (and) | Consider CT scan for increased sensitivity | |
Infection identified via culture or polymerase chain reaction, but clinical teamc believes this is not the sole cause of the underlying respiratory disease process OR minimum criteria to rule out pulmonary infection not met (testing not performed) and clinical teamc believes this is not the sole cause of the underlying respiratory disease process (and) | HIV testing SARS-CoV-2 testing Procalcitonin CBC with differential | |
No evidence in medical record of alternative plausible diagnoses (e.g., cardiac, rheumatologic, or neoplastic process). | Echocardiography Differential on CBC ANA RF ANCA ESR CRP |