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Table 2 ITIP3 fast-breathing pneumonia cohort and ITIP1 baseline characteristics

From: Malawian children with fast-breathing pneumonia with and without comorbidities

 

ITIP3 fast-breathing pneumonia cohort

ITIP1

HIVa,b

Malariaa,c

Severe acute malnutritiona,e

Anemiaa,d

Total

 

(n = 57)

(n = 20)

(n = 2)

(n = 17)

(n = 79)

(n = 1126)

Age (months)

 Median (IQR)

9 (5, 18)

19 (11, 24)

10 (10, 11)

18 (11, 24)

11 (6, 19)

18 (8, 32)

 2–6, n (%)

20 (35.1)

2 (10.0)

0 (0.0)

1 (5.9)

22 (27.8)

222 (19.7)

 7–11, n (%)

13 (22.8)

5 (25.0)

2 (100.0)

5 (29.4)

21 (26.6)

170 (15.1)

 12–23, n (%)

21 (36.8)

6 (30.0)

0 (0.0)

5 (29.4)

25 (31.6)

294 (26.1)

 24–35, n (%)

1 (1.8)

4 (20.0)

0 (0.0)

3 (17.6)

5 (6.3)

215 (19.1)

 36–59, n (%)

2 (3.5)

3 (15.0)

0 (0.0)

3 (17.6)

6 (7.6)

225 (20.0)

Sex

 Male, n (%)

28 (49.1)

12 (60.0)

1 (50.0)

9 (52.9)

40 (50.6)

525 (46.6)

 Female, n (%)

29 (50.9)

8 (40.0)

1 (50.0)

8 (47.1)

39 (49.4)

601 (53.4)

Respiratory ratef (breaths/minute)

 Age < 12 months

   < 50, n (%)

1 (3.0)

0 (0.0)

1 (50.0)

0 (0.0)

2 (4.7)

1 (0.3)

  50–59, n (%)

21 (63.6)

3 (429)

1 (50.0)

3 (50.0)

26 (60.5)

279 (71.2)

  60–69, n (%)

11 (33.3)

2 (28.6)

0 (0.0)

2 (33.3)

13 (30.2)

102 (26)

   ≥ 70, n (%)

0 (0.0)

2 (28.6)

0 (0.0)

1 (16.7)

2 (4.7)

10 (2.6)

 Age ≥ 12 months

   < 40, n (%)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

  40–49, n (%)

12 (50.0)

4 (30.8)

0 (0.0)

3 (27.3)

17 (47.2)

467 (63.6)

  50–59, n (%)

8 (33.3)

3 (23.1)

0 (0.0)

2 (18.2)

11 (30.6)

235 (32)

   ≥ 60, n (%)

4 (16.7)

6 (46.2)

0 (0.0)

6 (54.5)

8 (22.2)

32 (4.4)

Oxygen saturationg (%)

  < 90, n (%)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 90–92, n (%)

1 (1.8)

0 (0.0)

0 (0.0)

0 (0.0)

1 (1.3)

0 (0.0)

  ≥ 93, n (%)

56 (98.2)

20 (100.0)

2 (100.0)

17 (100.0)

78 (98.7)

1126 (100.0)

Axillary temperaturef (°C)

  ≥ 38, n (%)

16 (28.1)

16 (80.0)

1 (50.0)

14 (82.4)

31 (39.2)

335 (29.8)

  < 38, n (%)

41 (71.9)

4 (20.0)

1 (50.0)

3 (17.6)

48 (60.8)

791 (70.2)

Heart ratef (beats/minute)

 Median

146

159

148

160

151

147

 Minimum, Maximum

117, 179

141, 192

145, 152

141, 191

117, 192

101, 196

  1. aSubgroup based on data from screening/enrollment form; subgroups are not mutually exclusive
  2. bHIV defined as a positive HIV-1 rapid diagnostic test or HIV exposure
  3. cMalaria defined as a positive malaria rapid diagnostic test
  4. dAnemia defined as a hemoglobin < 8.0 g/dL
  5. eSevere acute malnutrition defined as MUAC < 115 mm or WFH z-score < −3
  6. fMaximum value between screening and enrollment
  7. g Minimum value between screening and enrollment