From: Malawian children with fast-breathing pneumonia with and without comorbidities
 | ITIP3 fast-breathing pneumonia cohort | ITIP1 | ||||
---|---|---|---|---|---|---|
HIVa,b | Malariaa,c | Severe acute malnutritiona,e | Anemiaa,d | Total | Â | |
(n = 57) | (n = 20) | (n = 2) | (n = 17) | (n = 79) | (n = 1126) | |
Age (months) | ||||||
 Median (IQR) | 9 (5, 18) | 19 (11, 24) | 10 (10, 11) | 18 (11, 24) | 11 (6, 19) | 18 (8, 32) |
 2–6, n (%) | 20 (35.1) | 2 (10.0) | 0 (0.0) | 1 (5.9) | 22 (27.8) | 222 (19.7) |
 7–11, n (%) | 13 (22.8) | 5 (25.0) | 2 (100.0) | 5 (29.4) | 21 (26.6) | 170 (15.1) |
 12–23, n (%) | 21 (36.8) | 6 (30.0) | 0 (0.0) | 5 (29.4) | 25 (31.6) | 294 (26.1) |
 24–35, n (%) | 1 (1.8) | 4 (20.0) | 0 (0.0) | 3 (17.6) | 5 (6.3) | 215 (19.1) |
 36–59, n (%) | 2 (3.5) | 3 (15.0) | 0 (0.0) | 3 (17.6) | 6 (7.6) | 225 (20.0) |
Sex | ||||||
 Male, n (%) | 28 (49.1) | 12 (60.0) | 1 (50.0) | 9 (52.9) | 40 (50.6) | 525 (46.6) |
 Female, n (%) | 29 (50.9) | 8 (40.0) | 1 (50.0) | 8 (47.1) | 39 (49.4) | 601 (53.4) |
Respiratory ratef (breaths/minute) | ||||||
 Age < 12 months | ||||||
   < 50, n (%) | 1 (3.0) | 0 (0.0) | 1 (50.0) | 0 (0.0) | 2 (4.7) | 1 (0.3) |
  50–59, n (%) | 21 (63.6) | 3 (429) | 1 (50.0) | 3 (50.0) | 26 (60.5) | 279 (71.2) |
  60–69, n (%) | 11 (33.3) | 2 (28.6) | 0 (0.0) | 2 (33.3) | 13 (30.2) | 102 (26) |
   ≥ 70, n (%) | 0 (0.0) | 2 (28.6) | 0 (0.0) | 1 (16.7) | 2 (4.7) | 10 (2.6) |
 Age ≥ 12 months | ||||||
   < 40, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
  40–49, n (%) | 12 (50.0) | 4 (30.8) | 0 (0.0) | 3 (27.3) | 17 (47.2) | 467 (63.6) |
  50–59, n (%) | 8 (33.3) | 3 (23.1) | 0 (0.0) | 2 (18.2) | 11 (30.6) | 235 (32) |
   ≥ 60, n (%) | 4 (16.7) | 6 (46.2) | 0 (0.0) | 6 (54.5) | 8 (22.2) | 32 (4.4) |
Oxygen saturationg (%) | ||||||
  < 90, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
 90–92, n (%) | 1 (1.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (1.3) | 0 (0.0) |
  ≥ 93, n (%) | 56 (98.2) | 20 (100.0) | 2 (100.0) | 17 (100.0) | 78 (98.7) | 1126 (100.0) |
Axillary temperaturef (°C) | ||||||
  ≥ 38, n (%) | 16 (28.1) | 16 (80.0) | 1 (50.0) | 14 (82.4) | 31 (39.2) | 335 (29.8) |
  < 38, n (%) | 41 (71.9) | 4 (20.0) | 1 (50.0) | 3 (17.6) | 48 (60.8) | 791 (70.2) |
Heart ratef (beats/minute) | ||||||
 Median | 146 | 159 | 148 | 160 | 151 | 147 |
 Minimum, Maximum | 117, 179 | 141, 192 | 145, 152 | 141, 191 | 117, 192 | 101, 196 |