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Table 1 Baseline and background characteristics and average percent adherence among enrolled children

From: Adherence to oral amoxicillin dispersible tablets in children with community-acquired pneumonia enrolled in clinical trials in Malawi

 

ITIP1

Average percent adherencea

ITIP2

Average percent adherencea

n = 1123

99.5

n = 2980

99.7%

Age (months)

 2–11, n (%)

392 (34.9%)

99.5

1728 (58.0%)

99.6

 12–35, n (%)

507 (45.1%)

99.5

1015 (34.1%)

99.8

 36–59, n (%)

224 (19.9%)

99.4

237 (8.0%)

99.7

 Mean (SD)

21.3 (15.0)

 

13.5 (12.2)

 

Gender

Male, n (%)

524 (46.7%)

99.5

1642 (55.1%)

99.7

Female, n (%)

599 (53.3%)

99.5

1338 (44.9%)

99.6

Mother’s highest level of education

None, n (%)

22 (2.0%)

100

100 (3.4%)

99.4

Primary, n (%)

497 (44.3%)

99.4

1698 (57.0%)

99.6

Secondary, n (%)

568 (50.6%)

99.5

1143 (38.4%)

99.8

Tertiary, n (%)

36 (3.2%)

100

39 (1.3%)

99.5

Any other children aged 0–10 years in same household

Yes

660 (58.8%)

99.3

1718 (57.7%)

99.7

No

463 (41.2%)

99.7

1262 (42.3%)

99.6

Ill for more than 24 h before entering study, n (%)

Yes

1061 (94.5%)

99.6

2610 (87.6%)

99.7

No

62 (5.5%)

98.4

370 (12.4%)

99.8

Axillary temperature ≥ 38 °C, n (%)

Yes

335 (29.8%)

99.8

920 (30.9%)

99.6

No

788 (70.2%)

99.4

2060 (69.1%)

99.7

Any concurrent diagnosis

Yes

374 (33.3%)

99.1

969 (32.5%)

99.5

No

749 (66.7%)

99.7

2011 (67.5%)

99.8

Any concomitant medication

Yes

744 (66.3%)

99.3

1935 (64.9%)

99.6

No

379 (33.7%)

99.8

1045 (35.1%)

99.8

Any concomitant antibiotic

Yes

33 (2.9%)

100

66 (2.2%)

99.7

No

1090 (97.1%)

99.5

2914 (97.8%)

99.7

Malaria, n (%)

Yes

141 (12.6%)

98.8

267 (9.0%)

99.4

No

982 (87.4%)

99.6

2713 (91.0%)

99.7

Moderate acute malnutrition, n (%)

Yes

18 (1.6%)

100

91 (3.1%)

99.6

No

1105 (98.4%)

99.5

2889 (96.9%)

99.7

Diarrhea, n (%)

Yes

104 (9.3%)

99.4

410 (13.8%)

99.1

No

1019 (90.7%)

99.5

2570 (86.2%)

99.8

  1. n number, SD Standard deviation
  2. a Average adherence = Caregiver reported percent of study drug doses taken of the possible doses provided prior to treatment failure