Table 1 Summary of the isolation and drug resistance profile of GNB in CAP
Country | Study year | Participants, age group, pneumonia category | Specimen | GNB (%) in culture | Frequently isolated GNB (%) | Decreasing order of resistance, MDR (%) | References |
|---|---|---|---|---|---|---|---|
Tanzania | 2015 | 353, adult, CAP | Sputum | 83.1% | K. pneumoniae (29.9%) and P. aeruginosa (11.7%) | K. pneumoniae: AMP > AMC > CRO P. aeruginosa: AMP/SXT/AMC > CRO > CIP | [39] |
China | 2016 to 2017 | 176, older (>  60 years), CAP | Sputum | 72.6% | K. pneumoniae (27.4%), E. coli (17.9%), and P. aeruginosa (10.3%) | K. pneumoniae: AMP > CXM > PIP, 25.0% ESBL E. coli: AMP > CXM > CTX > PIP, 42.9% ESBL P. aeruginosa: MIN > SXT > CXM | [26] |
Sudan | 2017 | 100, 16 to 60 years, CAP | Sputum | 76.2% | K. pneumoniae (42.8%) and P. aeruginosa (30.9%) | K. pneumoniae: CAZ/PEP/CRO/CTX, 16.7% ESBL P. aeruginosa: PIP > CL > IMP | [40] |
Ethiopia | 2018 | 414, adult, CAP | Sputum | 49.7% | K. pneumoniae (18.0%) and P. aeruginosa (11.4%) | K. pneumoniae: AMP/TE > AMC > SXT > C/DO > CN > CIP, 100% P. aeruginosa: CN > CRO > CIP > PIP > CAZ, 42.1% | [4] |
Ethiopia | 2020 | 406, ≥ 5 years, CAP | Sputum | 56.7% | K. pneumoniae (28.0%) and P. aeruginosa (14.0%) | K. pneumoniae: AMP > TE > SXT/AMC > C > AK > CAZ > PZP/CXM > CIP, 97.7% P. aeruginosa: CAZ > CN > TE/PEP/AK > CIP, 45.5% | [37] |
Ethiopia | 2021 | 312, adult, CAP | Sputum | 53.2% | K. pneumoniae (31.0%) and E. coli (20.7%) | K. pneumoniae: AMP > AMC > SXT > TE/DO, 94.9% E. coli: AMP > TE > DO > SXT > AMC, 93.8% | [38] |