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Table 3 Recent studies of vaccine efficacy of PPSV23

From: The remarkable history of pneumococcal vaccination: an ongoing challenge

 

Vaccine efficacy in pneumococcal pneumonia (PP)a

Author, year

All PP

VT PP

Comment

Suzuki 2017 [36]

27%

34%

CC, ≥ 65 years

Djennad 2019 [37]

27%

 

CC, ≥ 65 years

Kim 2019 [38]

 

21%

CC, 65–75 years

Lawrence 2020 [39]

 

24%

CC, persons ≥ 16 years

Vila-Corcoles 2020 [40]

0%

 

Pop-based cohort ≥ 50 years

Masuda 2021 [41]

61%

 

CC, ≥ 65 years, CRD

  1. PP Pneumococcal pneumonia, VT Vaccine-type, CC Case control study, Pop Population, CRD Chronic respiratory disease
  2. a Most of these studies show that protection decreases as age, and time since vaccination, increase