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Table 2 IPD, PP and ACP IRs by patient characteristics at the time of episode (2003–2019)

From: Incidence of pneumococcal disease from 2003 to 2019 in children ≤17 years in England

 

IPD

PP

ACP

N episodes

Rate per 100,000 PY (95% CI)

N episodes

Rate per 100,000 PY (95% CI)

N episodes

Rate per 100,000 PY (95% CI)

All individuals

170

2.29 (1.96–2.66)

769

10.34 (9.62–11.10)

12,142

163.37 (160.47–166.30)

Age groups

 0–1 years

101

15.52 (12.64–18.86)

195

29.97 (25.91–34.48)

3571

549.45 (531.57–567.77)

 2–4 years

36

2.86 (2.01–3.96)

265

21.08 (18.62–23.78)

4358

346.95 (336.73–357.41)

 5–17 years

33

0.60 (0.41–0.84)

309

5.59 (4.98–6.25)

4213

76.24 (73.95–78.57)

Sex

 Male

89

2.31 (1.86–2.85)

433

11.26 (10.22–12.37)

6543

170.22 (166.12–174.40)

 Female

81

2.26 (1.79–2.80)

336

9.36 (8.39–10.42)

5599

156.02 (151.96–160.17)

Geographic region

 North East

7

4.47 (1.80–9.22)

15

9.59 (5.37–15.81)

292

186.73 (165.93–209.43)

 North West

19

1.55 (0.93–2.42)

68

5.56 (4.31–7.04)

1881

153.75 (146.88–160.86)

 Yorkshire & The Humber

8

3.17 (1.37–6.24)

38

15.05 (10.65–20.66)

399

158.13 (142.99–174.43)

 East Midlands

11

5.73 (2.86–10.26)

7

3.65 (1.47–7.51)

471

245.56 (223.88–268.77)

 West Midlands

11

1.21 (0.61–2.17)

70

7.73 (6.02–9.76)

1557

171.90 (163.47–180.66)

 East of England

15

1.99 (1.11–3.28)

74

9.81 (7.70–12.32)

1042

138.19 (129.93–146.85)

 South West

27

3.13 (2.07–4.56)

126

14.63 (12.18–17.41)

1338

155.36 (147.15–163.92)

 South Central

33

3.33 (2.29–4.68)

119

12.02 (9.96–14.39)

1932

195.26 (186.65–204.16)

 London

16

1.71 (0.98–2.78)

123

13.17 (10.95–15.71)

1648

176.52 (168.10–185.26)

 South East Coast

23

1.97 (1.25–2.96)

129

11.08 (9.25–13.16)

1582

135.87 (129.26–142.73)

Urbanicity

 Urban

143

2.20 (1.86–2.60)

645

9.94 (9.19–10.74)

10,732

165.47 (162.36–168.63)

 Rural

27

2.85 (1.88–4.15)

124

13.10 (10.89–15.61)

1410

148.96 (141.28–156.94)

Social deprivation (IMD Score)a

 Quintile 1 (least deprived)

40

2.26 (1.61–3.07)

227

12.80 (11.19–14.58)

2657

149.90 (144.25–155.71)

 Quintile 2

28

1.87 (1.24–2.71)

134

8.96 (7.51–10.62)

2304

154.19 (147.95–160.61)

 Quintile 3

41

2.81 (2.01–3.81)

182

12.46 (10.71–14.40)

2429

166.31 (159.76–173.05)

 Quintile 4

30

2.21 (1.49–3.16)

126

9.30 (7.75–11.07)

2337

172.59 (165.66–179.73)

 Quintile 5 (most deprived)

31

2.30 (1.57–3.27)

100

7.43 (6.05–9.04)

2404

178.73 (171.66–186.02)

  1. aMissing values not reported. CI Confidence Interval, IMD Index of Multiple Deprivation, IPD Invasive Pneumococcal Disease, N Number, PY Person-Years