Skip to main content

Table 3 RIG-I-like receptors (RLR)

From: Innate immune responses in pneumonia

Name

Ligand

Location

Function

Signaling

Comment

Ref

RIG-I

Viral RNA

Cytoplasm

Interferon I and III production

MAVS

 

[56]

MDA5

Viral RNA

Cytoplasm

Interferon I and III production

MAVS

 

[56]

LGP2

Viral RNA

Cytoplasm

Unclear antiviral effect

None

Possible negative regulator of RIG-I and MDA5

[56]