Table 3 Performance of immunochromatographic test and culture compared with polymerase chain reaction to detect Streptococcus pneumoniae in pleural fluid

Point of care ICT at RRCCH

   All samples (n = 112)

100 (94.1–100)

86.3 (73.7–94.3)

89.7 (80.0–95.8)

100 (92.0–100)

   Samples from children with prior antibiotic use^a (n = 58)

100 (89.1–100)

92.3 (74.9–99.0)

94.1 (80.3–99.3)

100 (85.8–100)

Repeat ICT at CDC

   All samples^b (n = 101)

98.2 (90.3–100)

97.8 (88.5–99.9)

98.2 (90.3–100)

97.8 (88.5–99.9)

   Samples from children with prior antibiotic use^a (n = 53)

96.6 (82.2–99.9)

100 (85.8–100)

100 (87.8–100)

97.8 (88.5–99.9)

Culture

   All samples (n=112)

29.5 (18.5–42.6)

100 (93.0–100)

100 (81.5–100)

54.3 (43.7–64.6)

   Samples from children with prior antibiotic use^a (n = 58)

9.4 (2.0–25.0)

100 (86.8–100)

100 (29.2–100)

47.3 (33.6–61.2)