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Table 1 Potential therapeutic/preventative strategies targeting cardiac events in patients with community-acquired pneumonia

From: Prevalence, pathogenesis, therapy, and prevention of cardiovascular events in patients with community-acquired pneumonia

• Anti-platelet agents

 

 o inhibitors of production of thromboxane A2

 

 o antagonists of thromboxane A2 receptors

 

 o antagonists of ADP-activated P2Y12 receptors

 

 o antagonists of thrombin-activated proteinase-activated receptor 1

 

 o GPIIb/IIIa inhibitors

 

• Agents targeting pneumolysin

 

 o macrolides

 

 o statins

 

 o cholesterol-rich liposomes

 

• Immunisation

 

 o PCV 13 with or without immunogenic pneumolysoid

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