Drug-resistant tuberculosis and advances in the treatment of childhood tuberculosis

Pneumonia

Table 2 Suggested schedule of follow up for children on treatment for multidrug-resistant tuberculosis

All children	Baseline	Month										Ongoing
All children	Baseline	1	2	3	4	5	6	9	12	15	18
HIV status	•
Toxicity (symptoms, signs)	•	•	•	•	•	•	•	•	•	•	•	•
Height and weight	•	•	•	•	•	•	•	•	•	•	•	•
Audiology^a	•	•	•	•	•	•	•
Colour vision testing^b	•	•	•	•	•	•	•	•	•	•	•	•
Chest radiograph^c	•			•			•
TB culture and DST^d	•	•	•	•	•	•	•
Creatinine and potassium^a	•	•	•	•	•	•	•
TSH, free T₄ ^e	•			•			•	•	•	•	•	•
Haematology (FBC)^f	•	•	•		•		•	•	•	•	•	•
ECG^g	•	•	•		•		•	•	•	•	•	•
HIV-positive
LFTs, Cholesterol	•						•			•		•
CD4 count and viral load	•						•			•		•

DST drug susceptibility test, TSH thyroid stimulating hormone, ECG electrocardiogram, LFTs liver function tests
^aMonthly whilst on an injectable and at 6 months following termination of injectable
^bIf on ethambutol or linezolid
^cIf any pulmonary involvement or at any point if clinically indicated; to be repeated at the end of treatment
^dMonthly if old enough to expectorate. If unable to expectorate and initially smear or culture positive, monthly until culture-converted then 3 monthly. If initially smear and culture negative, to perform if clinically indicated
^eif on ethionamide, prothionamide or PAS
^fif on linezolid or if HIV-positive
^gif on bedaquiline or delamanid

ISSN: 2200-6133