Pneumonia

Table 3 Bivariate analysis of clinical and diagnostic factors associated with non-adherence at 80% and 100% completion

From: Non-adherence to community oral-antibiotic treatment in children with fast-breathing pneumonia in Malawi– secondary analysis of a prospective cohort study

		80% adherence					100% adherence
		Adherent	Non-adherent	OR	p-value	95% CI	Adherent	Non-adherent	OR	p-value	95% CI
Fever^a	Normal	493	45				432	106
Fever^a	High	234	31	1.45	0.129	0.89, 2.36	208	57	1.12	0.549	0.78, 1.60
Oxygen Saturation^b	Normal	643	66				566	134
Oxygen Saturation^b	Abnormal	113	13	1.11	0.754	0.59, 2.07	93	33	1.50	0.070	0.96, 2.33
Respiratory Rate^c	High	680	75				599	156
Respiratory Rate^c	V.High	40	3	0.68	0.526	0.21, 2.25	35	8	0.88	0.745	0.40, 1.93
Heart Rate^d	Normal	541	60				477	112
Heart Rate^d	High	182	16	0.79	0.429	0.45, 1.41	162	48	1.26	0.232	0.86, 1.85
Clinical Malaria	No	453	36				408	81
Clinical Malaria	Yes	302	43	1.79	0.013	1.12, 2.86	259	86	1.67	0.003	1.19, 2.36
Diarrhoea	No	733	73				648	158
Diarrhoea	Yes	22	6	2.74	0.028	1.07, 6.99	19	9	1.94	0.103	0.86, 4.38
Any Concurrent Diagnosis	No	397	26				361	62
Any Concurrent Diagnosis	Yes	358	53	2.26	0.001	1.38, 9.71	306	105	2.00	0.001	1.40, 2.82
LA^e	No	377	27				340	64
LA^e	Yes	378	52	1.92	0.008	1.80, 3.13	327	103	1.67	0.004	1.18, 2.37
Paracetamol	No	381	23				342	62
Paracetamol	Yes	374	56	2.48	0.001	1.49, 4.13	325	105	1.78	0.001	1.25, 2.53
Multiple Drugs	No	300	19				269	50
Multiple Drugs	Yes	455	60	2.08	0.006	1.21, 3.57	398	117	1.58	0.013	1.10, 2.28
Duration of illness	<24h	450	32				408	74
Duration of illness	>24h	301	46	2.15	0.001	1.33, 3.46	255	92	1.99	0.001	1.41, 2.82
Vomited after antibiotics	No	658	68				581	145
Vomited after antibiotics	Yes	96	10	1.01	0.982	0.50, 2.03	85	21	0.99	0.969	0.59, 1.65
Age	2–11mths	233	35				213	55
	12–23mths	247	26	0.70	0.195	0.41, 1.20	210	63	1.16	0.472	0.77, 1.75
	24–59mths	275	18	0.44	0.006	0.24, 0.79	244	49	0.79	0.248	0.52, 1.21
Sex	Male	355	36				311	80
Sex	Female	386	43	0.91	0.693	0.57, 1.45	342	87	1.01	0.949	0.72, 1.42

^aNormal: <=37.4 °C, High: > 37.4 °C ; ^bNormal: = > 95% Abnormal: <= 94%; ^cHigh: 40–59 (age 12–59 months) 50–69 (age 2–11 months), Very High: > = 60 (age 12–59 months) > =70 (age 2–11 months); ^dNormal: <159 (age 2–11months), <149 (age 12–23 months), <139 (age 24–59 months). LA: Lumefantrine Artemether
^eLumefantrine Artemether prescribed by the community health worker

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ISSN: 2200-6133

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