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Table 6 Outcome depending on relevant detected pathogen for pediatric patients

From: Impact of viral multiplex real-time PCR on management of respiratory tract infection: a retrospective cohort study

  Viral Bacterial Mixed No pathogen p-value a
(n = 40) (n = 6) (n = 5) (n = 21) Viral vs. bacterial Viral vs. mixed Viral vs. no pathogen
LOS inpatients, median days (IQR) 18.5 (6–48.75) 47.5 (14–95.75) 34 (17.5–201.5) 37 (8–70) 0.19 0.10 0.45
 Complications, n (%)
  ICU admission 18 (45.0) 4 (66.7) 5 (100.0) 12 (57.1) 0.58 0.06 0.37
  Mechanical ventilation 8 (20.0) 4 (66.7) 4 (80.0) 11 (52.4) 0.07 0.03 0.01
  ARDS 1 (2.5) 0 (0.0) 1 (20.0) 0 (0.0) 1.00 0.42 1.00
  Sepsis 17 (42.5) 4 (66.7) 2 (40.0) 0 (0.0) 0.50 1.00 n/a
  Mortality (all cause) 2 (5.0) 0 (0.0) 0 (0.0) 0 (0.0) 1.00 1.00 0.85
 Antibiotic use (any indication)
  Any inpatient antibiotics, n (%) 28/38 (73.7) 6/6 (100.0) 5/5 (100.0) 18/20 (90.0) 0.38 0.49 0.26
  Duration of inpatient use, mean days ± SD (range) 8.6 ± 13.4 (0–73) 14.2 ± 11.0 (0–34) 13.8 ± 7.8 (7–24) 6.2 ± 4.8 (0–18) 0.34 0.40 0.33
  Discharged receiving oral antibiotics, n (%) 6 (15.8)b 0 (0.0) 1 (20.0) 3 (15.0)c 0.78 1.00 1.00
  1. ARDS acute respiratory distress syndrome, ICU intensive care unit, IQR interquartile range, LOS length of stay, n number, SD standard deviation
  2. aFor continuous variables, 2-sample independent t-test or Mann-Whitney-U-test were used. For categorical variables, Mantel-Haenszel chi square or Fisher exact test were used
  3. Missing values due to death or ongoing hospitalisation at time of analysis (number): b2; c1. For calculation of percentage and p-value missing values were excluded