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Table 3 Number of collected specimens (% of participants seen at specified age), blood volumes and PBMCsa isolated at study visits

From: Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea

Age

1 month

4 months

9 months

10 months

23 months

24 months

Study participantsb

262

222

208

201

182

176

Nasopharyngeal swabs

262 (100%)

215 (97%)

205 (99%)

199 (99%)

182 (100%)

175 (99%)

Blood (serum)

262 (100%)

213 (96%)

201 (97%)

196 (98%)

182 (100%)

175 (99%)

Mean volume (mL)

1.8

2.3

2.3

2.2

2.4

2.3

(Min-Max)

(0.1–5.0)

(0.2–5.0)

(0.2–5.0)

(0.1–4.0)

(0.5–4.0)

(0.3–4.0)

Blood (PBMCsa)

–

142 (64%)

143 (69%)

128 (64%)

126 (69%)

119 (68%)

Mean volume (mL)

–

1.9

2.0

1.9

1.9

1.8

(Min-Max)

 

(0.1–4.5)

(0.5–4.0)

(0.4–4)

(0.3–4.0)

(0.3–3.0)

Mean number of cells ×10 6 (95% CI)

 

8.5 (7.3–9.6)

10.1 (8.8–11.4)

9.4 (8.3–10.4)

8.7 (7.5–9.8)

8.8 (7.7–10.0)

  1. aPeripheral blood mononuclear cells bNumbers exclude those who did not meet inclusion criteria and those who were lost to follow-up or withdrawn
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Pneumonia

ISSN: 2200-6133

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