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Table 3 Comparison of subjects “pre-treated” with antibiotics prior to admission against those not “pre-treated”

From: The association between pre-hospital antibiotic therapy and subsequent in-hospital mortality in adults presenting with community-acquired pneumonia: an observational study

 

Not pre-treated with antibiotics pre-admission (n = 4973)

Pre-treated with antibiotics pre-admission (n = 1059)

P value

Age

72.41 (16.71)

72.13 (15.88)

0.61

Gender

 Female

2484 (49.9%)

564 (53.3%)

0.051

 Male

2498 (50.1%)

495 (46.7%)

In-hospital Mortality

658 (13)

197 (19)

< 0.001

Length Of Stay (LOS)

5 (2–11)

5 (3–11)

0.15

Admission CURB-65 score (n = 3993; 2355 cases not documented)

CURB 0:463 (14%)

CURB 0: 84 (14%)

0.72

CURB 1: 780 (23%)

CURB 1: 126 (21%)

CURB 2: 1073(32%)

CURB 2: 196 (32%)

CURB 3: 830 (25%)

CURB 3: 162 (27%)

CURB 4: 211(6%)

CURB 4: 33 (5%)

CURB 5: 29 (1%)

CURB 5: 6 (1%)

Charlson Co-morbidity Index

4 (3–16)

7 (3–17)

0.001

History of MI

489 (9.8)

109 (10.3)

0.65

History of CVA

248 (5)

63 (5.9)

0.20

History of CCF

792 (15.1)

197 (18.6)

0.005

History of Pulmonary Disease

2314 (46.5)

498 (47)

0.78

History of Renal Disease

709 (14.3)

190 (17.9)

0.002

History of Diabetes Mellitus

922 (18.5)

183 (17.3)

0.34

History of Diabetes Mellitus with complications

54 (1.1)

11 (1)

0.89

History of Dementia

578 (11.6)

144 (13.6)

0.07

History of Paraplegia

93 (1.9)

25 (2.4)

0.30

History of Liver Disease

49 (1)

4 (0.4)

0.054

History of Severe Liver Disease

20 (0.4)

3 (0.3)

0.57

History of Cancer

633 (12.7)

133 (12.6)

0.88

History of Metastatic Cancer

224 (4.5)

48 (4.5)

0.97