Table 1 Baseline characteristics of the study population
All individuals | 916,805 | |
|---|---|---|
Year (n) | ||
2014 | 683,807 | |
2015 | 682,618 | |
2016 | 673,787 | |
2017 | 662,069 | |
2018 | 654,311 | |
2019 | 646,472 | |
Age (years) at study entry (mean, SD) | 6 | 5.22 |
Age group (n, %) | ||
0–1 | 306,767 | 33.46 |
2–4 | 126,764 | 13.83 |
5–15 | 483,274 | 52.71 |
Sex (n, %) | ||
Male | 471,991 | 51.48 |
Female | 444,814 | 48.52 |
Underlying medical conditions for 2015 cohort* (n, %) | ||
No at-risk medical condition | 609,198 | 89.24 |
Any at-risk medical condition | 67,001 | 9.82 |
Chronic diseases | ||
Diabetes mellitus | 2,089 | 0.31 |
Chronic pulmonary disease (incl. asthma) | 48,728 | 7.14 |
Chronic heart disease | 11,535 | 1.69 |
Neurological disorders | 8,195 | 1.20 |
Any high-risk medical condition | 9,359 | 1.37 |
Cancer | 931 | 0.14 |
Cerebrospinal fluid leak | 8 | 0.00 |
Chronic renal disease | 848 | 0.12 |
Cochlear implant | 1,078 | 0.16 |
Functional or anatomic asplenia, sickle cell disease/other hemoglobinopathy, congenital or acquired asplenia, splenic dysfunction, splenectomy | 737 | 0.11 |
HIV infection | 27 | 0.00 |
Immuno-compromising diseases | 5,287 | 0.77 |
Organ transplant | 431 | 0.06 |
Chronic liver disease | 408 | 0.06 |
Autoimmune disease | 368 | 0.05 |