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Table 6 Antibiotic prescription rate in outpatient care associated with pneumonia, IPD and AOM from 2014 to 2019

From: Healthcare resource utilization and cost of pneumococcal disease in children in Germany, 2014–2019: a retrospective cohort study

 

2014

2015

2016

2017

2018

2019

Trend test

(p-value)

PP

 N patients

29

18

27

28

23

32

 

 Rate per 1,000 PY

5,180

6,525

6,181

5,968

5,598

5,549

0.452

 95% CI

3,869–6,793

4,491–9,163

4,602–8,127

4,565–7,666

4,141–7,401

4,334–7,000

 

ACP

 N patients

11,977

10,712

10,932

9,256

8,328

7,466

 

 Rate per 1,000 PY

6,363

5,893

6,125

5,750

5,367

5,380

0.060

 95% CI

6,274–6,454

5,804–5,983

6,033–6,218

5,655–5,846

5,273–5,462

5,280–5,482

 

IPD

 N patients

NA

6

NA

8

NA

NA

 

 Rate per 1,000 PY

-

4,490

-

3,185

-

-

1

 95% CI

 

2,616–7,189

 

1,887–5,033

   

AOM

 N patients

45,636

44,148

43,050

38,830

37,348

35,269

 

 Rate per 1,000 PY

27,097

26,909

27,230

26,774

26,636

26,536

0.060

 95% CI

26,894–27,300

26,703–27,117

27,018–27,444

26,552–26,998

26,410–26,865

26,302–26,771

 

AOM simple

 N patients

43,852

42,574

41,480

37,459

36,145

34,223

 

 Rate per 1,000 PY

27,247

27,092

27,465

26,997

26,842

26,761

0.060

 95% CI

27,024–27,472

26,866–27,320

27,233–27,699

26,755–27,241

26,597–27,089

26,510–27,014

 

AOM recurrent

 N patients

4,983

4,562

4,273

3,656

3,268

2,546

 

 Rate per 1,000 PY

26,372

25,966

25,962

25,511

25,357

24,987

0.009

 95% CI

25,892–26,859

25,465–26,474

25,439–26,493

24,953–26,079

24,765–25,960

24,353–25,632