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Table 3 Clinical management and outcome of children with respiratory symptoms who were hospitalised, before and after the intervention

From: Clinical algorithm reduces antibiotic use among children presenting with respiratory symptoms to hospital in central Vietnam

Management and outcome

Before

N = 38

After

N = 13

p-value

Department admitted to

 Infectious diseases

36 (94.7)

12 (92.3)

-

 Respiratory

2 (5.3)

1 (7.7)

-

Reason for admission*

 Underlying co-morbid conditionsa

5 (12.2)

0

-

 Parental worries

1 (2.4)

0

-

 Unresponsive to first line treatment

19 (46.3)

8 (61.5)

-

 Danger signsb and Sp02 < 92%

7 (17.0)

1 (7.7)

-

 Othersc

9 (22.1)

4 (30.8)

-

Clinical signs and symptoms

 Fast breathingd

24 (63.2)

5 (38.5)

0.19

 Sp02 < 92%

7 (18.4)

1 (7.7)

0.66

 Danger signsb

2 (5.3)

1 (7.7)

1.00

 Fevere

24 (63.2)

10 (76.9)

0.50

 Wheezef

10 (26.3)

2 (15.4)

0.71

Chest radiograph findings

38 (100.0)

13 (100.0)

-

 Normal

13 (34.2)

7 (53.8)

0.32

 Consolidation/patchy infiltration

16 (42.1)

2 (15.4)

0.10

 Other abnormalities

9 (23.7)

4 (30.8)

0.72

Blood neutrophil count

38 (100.0)

13 (100.0)

-

  < 5,000 g/l

13 (34.2)

7 (53.8)

0.32

 5–10,000 g/l

15 (39.5)

3 (23.1)

0.34

  > 10,000 g/l

10 (26.3)

3 (23.1)

1.00

CRP

36 (94.7)

13 (100.0)

-

  < 50 g/l

30 (83.3)

10 (76.9)

0.68

  ≥ 50 mg/l

6 (16.7)

3 (23.1)

 

Diagnosis at admission

 Pneumonia

25 (65.8)

6 (46.2)

0.32

 Asthma

1 (2.6)

0 (0)

-

 Bronchiolitis

9 (23.7)

1 (7.6)

-

 URTI

3 (7.9)

6 (46.2)

 < 0.001

Diagnosis at discharge

 Pneumonia

24 (63.2)

6 (46.2)

0.34

 Asthma

1 (2.6)

0 (0)

-

 Bronchiolitis

8 (21.1)

0 (0)

-

 URTI

5 (13.1)

7 (53.8)

 < 0.001

Treatment

 Oral antibiotics

26 (72.2)

7 (53.8)

0.50

 IV antibiotics

6 (16.7)

1 (7.6)

0.66

 No antibiotics

4 (11.1)

5 (38.6)

0.04

Readmission within 1 week

1 (2.6)

0 (0)

-

  1. Sp02 peripheral oxygen saturation, CRP C-reactive protein. URTIs upper respiratory tract infections, IV intravenous
  2. *More than 1 reason possible
  3. asuch as congenital heart disease, or immunocompromise
  4. binability to breastfeed or drink from bottle, vomiting everything, lethargy or reduced level of consciousness, convulsions, respiratory distress (grunting or nasal flaring), severe stridor, severe malnutrition
  5. chigh fever and cough, abnormal blood test results defined as breath rate of ≥ 50/minute aged 2–11 months, or ≥ 40/minute aged 12–59 months [13]
  6. etemperature ≥ 38.50C on admission
  7. faudible wheeze or wheeze on auscultation