Table 2 Incidence rates of new-onset LRTI after index hospitalization by reason for hospitalizationa
N | Events | Person-Years | Incidence per 1000 person-years (95% CI) | 365-day Cumulative Incidence (95% CI)b | |
|---|---|---|---|---|---|
Full Cohort | |||||
Non-LRTI | 176,788 | 8878 | 169,245.910 | 52.5 (51.4,53.6) | 6.4% (6.2%, 6.5%) |
COVID-19 LRTI | 22,417 | 1348 | 24,345.871 | 55.4 (52.5,58.4) | 7.0% (6.6%, 7.4%) |
Non-COVID-19 LRTI | 12,795 | 2516 | 9926.175 | 253.5 (243.7,263.6) | 24% (23%, 24%) |
Age ≥ 65 years | |||||
Non-LRTI | 84,398 | 6078 | 79,600.660 | 76.4 (74.4,78.3) | 8.9% (8.6%, 9.1%) |
COVID-19 LRTI | 8765 | 761 | 9110.926 | 83.5 (77.7,89.7) | 10% (9.5%, 11%) |
Non-COVID-19 LRTI | 8738 | 1802 | 6487.975 | 277.7 (265.1,290.9) | 25% (24%, 26%) |
Age < 65 years | |||||
Non-LRTI | 92,390 | 2800 | 89,645.25 | 31.2 (30.1,32.4) | 3.9% (3.8%, 4.1%) |
COVID-19 LRTI | 13,652 | 587 | 15,234.95 | 38.5 (35.5,41.8) | 5.0% (4.6%, 5.4%) |
Non-COVID-19 LRTI | 4057 | 714 | 3438.20 | 207.7 (192.7,223.5) | 21% (19%, 22%) |
ICU during index hospitalization | |||||
Non-LRTI | 14,028 | 814 | 13,828.277 | 58.9 (54.9,63.1) | 7.2% (6.7%, 7.7%) |
COVID-19 LRTI | 2314 | 144 | 2445.827 | 58.9 (49.7,69.3) | 7.4% (6.3%, 8.6%) |
Non-COVID-19 LRTI | 1319 | 253 | 1112.603 | 227.4 (200.2,257.2) | 23% (20%, 26%) |
No ICU during index hospitalization | |||||
Non-LRTI | 162,760 | 8064 | 155,417.633 | 51.9 (50.8,53) | 6.3% (6.1%, 6.4%) |
COVID-19 LRTI | 20,103 | 1204 | 21,900.044 | 55 (51.9,58.2) | 6.9% (6.6%, 7.3%) |
Non-COVID-19 LRTI | 11,476 | 2263 | 8813.573 | 256.8 (246.3,267.6) | 24% (23%, 25%) |
ACIP high risk | |||||
Non-LRTI | 34,308 | 3419 | 30,568.468 | 111.8 (108.1,115.7) | 12% (12%, 13%) |
COVID-19 LRTI | 3618 | 407 | 3549.384 | 114.7 (103.8,126.4) | 14% (12%, 15%) |
Non-COVID-19 LRTI | 4085 | 949 | 2954.408 | 321.2 (301.1,342.3) | 28% (26%, 29%) |
ACIP medium risk | |||||
Non-LRTI | 65,056 | 3699 | 62,371.378 | 59.3 (57.4,61.2) | 7.2% (7.0%, 7.4%) |
COVID-19 LRTI | 8242 | 536 | 9093.688 | 58.9 (54.1,64.1) | 7.5% (6.9%, 8.2%) |
Non-COVID-19 LRTI | 5325 | 1093 | 4147.288 | 263.5 (248.2,279.6) | 25% (24%, 26%) |
ACIP low risk | |||||
Non-LRTI | 77,424 | 1760 | 76,306.063 | 23.1 (22,24.2) | 2.9% (2.8%, 3.1%) |
COVID-19 LRTI | 10,557 | 405 | 11,702.800 | 34.6 (31.3,38.1) | 4.4% (4.0%, 4.8%) |
Non-COVID-19 LRTI | 3385 | 474 | 2824.479 | 167.8 (153,183.6) | 16% (15%, 18%) |