Variable | CAP N = 124, N (%) | P-CAP N = 57, N (%) | Non P-CAP N = 67, N (%) | p |
---|---|---|---|---|
Demographic data | ||||
Age (years)* | 70.5 (57–81) | 68 (53.5–79) | 74 (57–83) | 0.15 |
Gender, male | 78 (62.9) | 39 (68.4) | 39 (58.2) | 0.24 |
Current smoker | 31 (25) | 16 (28.1) | 15 (22.4) | 0.47 |
Former smoker | 45 (36.3) | 22 (38.6) | 23 (34.3) | 0.62 |
Alcohol abuse | 17 (13.7) | 7 (12.3) | 10 (14.9) | 0.67 |
BMI, mean (SD) | 26.6 (4.76) | 25.6 (4.6) | 27.1 (4.8) | 0.09 |
Influenza vaccine | 50 (40.3) | 22 (38.6) | 28 (41.8) | 0.72 |
Pneumococcal vaccine | 17 (13.7) | 7 (12.3) | 10 (14.9) | 0.67 |
Comorbid conditions | ||||
Charlson score* | 1 (0–2) | 1 (0–2.5) | 1 (0–2) | 0.66 |
Immunosuppression 1 | 5 (4) | 3 (5.26) | 2 (2.99) | 0.66 |
Prior antibiotic treatment 2 | 19 (15.3) | 6 (10.5) | 13 (19.4) | 0.17 |
Pre-hospital antibiotic treatment 3 | 18 (14.5) | 8 (14) | 10 (14.9) | 0.89 |
Clinical features on presentation | ||||
Time from symptom onset to ED visit (hours)* | 72 (48–120) | 48 (24–96) | 72 (48–144) | 0.01 |
Fever (≥ 38 °C) | 51 (41.1) | 28 (50.9) | 23 (34.3) | 0.1 |
Dyspnoea | 90 (72.6) | 39 (68.4) | 51 (76.1) | 0.34 |
Tachypnea (≥ 20 rpm) | 87 (78.4) | 44 (83) | 43 (74.1) | 0.26 |
Cough | 109 (87.9) | 52 (91.2) | 57 (85.1) | 0.3 |
Purulent sputum | 55 (44.4) | 22 (38.6) | 33 (49.3) | 0.23 |
Pleuritical chest pain | 43 (34.7) | 28 (49.1) | 15 (22.4) | 0.002 |
Septic shock | 20 (16.3) | 12 (21.1) | 8 (12.2) | 0.18 |
Respiratory failure | 73 (59.4) | 32 (56.1) | 41 (62.1) | 0.5 |
Severe CAP 4 | 23 (18.5) | 12 (21.1) | 11 (16.4) | 0.68 |
PSI classes* | 3 (2–4) | 4 (3–4) | 3 (2–4) | 0.42 |
CURB-65 score* | 1 (1–2) | 2 (1–2) | 1 (1–2) | 0.29 |
Co-infection | 39 (31.5) | 29 (50.9) | 10 (14,9) | < 0.001 |
Evolution and Outcome | ||||
Time to clinical stability (days)* | 2 (1–4) | 2 (1–4) | 2 (1–3.5) | 0.33 |
ICU admission | 11 (8.87) | 4 (7.02) | 7 (10.5) | 0.51 |
Need for mechanical ventilation | 6 (5.84) | 1 (1.75) | 5 (7.46) | 0.28 |
Length of hospital stay (days)* | 6 (3–10) | 6 (4.5–9) | 6 (2–10) | 0.78 |
In-hospital mortality | 1 (0.81) | 0 | 1 (1.49) | 1 |