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Table 2 Semi-quantitative scores for grading the severity of pathologic lesions of the lungs

From: Sex-dependent vulnerability for Wistar rats model following intranasal instillation with Klebsiella pneumoniae ATCC 43816 causing lobar pneumonia

Tissue

Histologic changes

Score

Lymphatic nodule

No change

0

Leukocyte infiltration into inflamed lung tissue (Inflammatory granuloma forming)

 + 1

Mild inflammatory granuloma without alveolar alterations

 + 2

Severe inflammatory granuloma with the destruction of alveoli (lung abscess)

 + 3

Severe inflammatory granuloma with the destruction of alveoli and peribronchial inflammation with luminal slough

 + 4