Acute fibrinous and organising pneumonia following lung transplantation is associated with severe allograft dysfunction and poor outcome: a case series

Table 2 Bronchoalveolar lavage (BAL) fluid analysis and transbronchial lung biopsy (TBB) findings (performed when acute fibrinous and organising pneumonia [AFOP] was diagnosed)

Case	BAL									TBB grade
	Cells/µl	Neutrophils (%)	Lymphocytes (%)	Eosinophils (%)	Macrophages (%)	Microbiology
						Gram stain	Bacterial culture		Other^a
							Bacteria	Concentration (cfu/µl)
1	2,130	69	4	1	23	No bacteria	Oral flora	<10³	None	A0B0 AFOP
2	875	48	0	0	6	Bacteria present	MSSA mucoid Pseudomonas aeruginosa	4 × 10⁴ 3 × 10⁴	None	A0B0 AFOP
3	295	15	53	0	30	No bacteria	NG		None	A0B0 AFOP
4	330	44	27	1	26	No bacteria	Stenotrophomonas maltophilia	8 × 10³	Aspergillus fumigatus (Galactomannan negative)	A0B0 AFOP
5	188	28	16	4	49	No bacteria	NG		Cytomegalovirus PCR positive	A0B0 AFOP
6	200	10	38	8	40	Rare bacteria	MSSA	2 × 10⁴	None	A1B1 AFOP

cfu, colony forming units; MSSA, methicillin-sensitive Staphylococcus aureus; NG, no growth; PCR, polymerase chain reaction
^aAll BAL specimens were evaluated (stains/cultures/PCR) for Pneumocystis jiroveci and other fungi, bacterial pathogens (quantitative), viruses (cytomegalovirus, herpes simplex, respiratory syncytial virus, influenza, parainfluenza, metapneumovirus, rhinovirus, and adenovirus), mycobacteria, and Nocardia spp.

ISSN: 2200-6133