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  1. Case report

    Case report on a defective antibody response against pneumococcal serotype 9V in a patient with a single episode of pneumonia

    Patients with recurrent respiratory tract infections and an impaired response to pneumococcal polysaccharide vaccination are diagnosed with a specific antibody deficiency. In adult patients with pneumococcal p...

    Diana van Kessel, Thijs Hoffman, Heleen van Velzen-Blad, Bob Meek, Suzan van Mens, Jan Grutters and Ger Rijkers

    Pneumonia 2017 9:16

    Published on: 5 November 2017

  2. Commentary

    Community-acquired pneumonia in the United Kingdom: a call to action

    Pneumococcal disease has a high burden in adults in the United Kingdom (UK); however, the total burden is underestimated, principally because most cases of community-acquired pneumonia (CAP) are non-invasive. ...

    James Chalmers, James Campling, Gillian Ellsbury, Peter M. Hawkey, Harish Madhava and Mary Slack

    Pneumonia 2017 9:15

    Published on: 5 October 2017

  3. Research

    Predictors of pneumococcal carriage and the effect of the 13-valent pneumococcal conjugate vaccination in the Western Australian Aboriginal population

    The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced to prevent invasive pneumococcal disease (IPD) in Western Australian (WA) Aboriginal people in 2001. PCV13 replaced PCV7 in July 2011, covering...

    Deirdre A. Collins, Anke Hoskins, Thomas Snelling, Kalpani Senasinghe, Jacinta Bowman, Natalie A. Stemberger, Amanda J. Leach and Deborah Lehmann

    Pneumonia 2017 9:14

    Published on: 25 September 2017

  4. Brief report

    Pharmacologic inhibition of MEK1/2 reduces lung inflammation without impairing bacterial clearance in experimental Pseudomonas aeruginosa pneumonia

    This study was designed to test the therapeutic potential of a MEK1/2 inhibitor (MEKi) in an experimental model of Pseudomonas aeruginosa pneumonia. The study found that treatment with MEKi reduced alveolar neutr...

    Matthew E. Long, Ke-Qin Gong, William E. Eddy, W. Conrad Liles and Anne M. Manicone

    Pneumonia 2017 9:13

    Published on: 5 September 2017

  5. Review

    Atypical bacterial pneumonia in the HIV-infected population

    Human immunodeficiency virus (HIV)-infected individuals are more susceptible to respiratory tract infections by other infectious agents (viruses, bacteria, parasites, and fungi) as their disease progresses to ...

    Breanne M. Head, Adriana Trajtman, Zulma V. Rueda, Lázaro Vélez and Yoav Keynan

    Pneumonia 2017 9:12

    Published on: 25 August 2017

  6. Review

    Necrotizing pneumonia: an emerging problem in children?

    In children, necrotizing pneumonia (NP) is an uncommon, severe complication of pneumonia. It is characterized by destruction of the underlying lung parenchyma resulting in multiple small, thin-walled cavities ...

    I. Brent Masters, Alan F. Isles and Keith Grimwood

    Pneumonia 2017 9:11

    Published on: 25 July 2017

  7. Review

    Pneumococcal conjugate vaccine implementation in middle-income countries

    Since 2000, the widespread adoption of pneumococcal conjugate vaccines (PCVs) has had a major impact in the prevention of pneumonia. Limited access to international financial support means some middle-income c...

    Serena Tricarico, Hannah C. McNeil, David W. Cleary, Michael G. Head, Victor Lim, Ivan Kok Seng Yap, Chong Chun Wie, Cheng Siang Tan, Mohd Nor Norazmi, Ismail Aziah, Eddy Seong Guan Cheah, Saul N. Faust, Johanna M.C. Jefferies, Paul J. Roderick, Michael Moore, Ho Ming Yuen…

    Pneumonia 2017 9:6

    Published on: 25 March 2017

  8. Research

    Childhood pneumonia and meningitis in the Eastern Highlands Province, Papua New Guinea in the era of conjugate vaccines: study methods and challenges

    Pneumonia and meningitis are common causes of severe childhood illness in Papua New Guinea (PNG). The etiology of both clinical conditions in PNG has not been recently assessed. Changes in lifestyle, provision...

    Christopher C. Blyth, Rebecca Ford, Joycelyn Sapura, Tonny Kumani, Geraldine Masiria, John Kave, Lapule Yuasi, Andrew Greenhill, Ilomo Hwaihwanje, Amanda Lang, Deborah Lehmann and William Pomat

    Pneumonia 2017 9:5

    Published on: 5 March 2017

  9. Research

    Increased risk of pneumonia in residents living near poultry farms: does the upper respiratory tract microbiota play a role?

    Air pollution has been shown to increase the susceptibility to community-acquired pneumonia (CAP). Previously, we observed an increased incidence of CAP in adults living within 1 km from poultry farms, potenti...

    Lidwien A. M. Smit, Gert Jan Boender, Wouter A. A. de Steenhuijsen Piters, Thomas J. Hagenaars, Elisabeth G. W. Huijskens, John W. A. Rossen, Marion Koopmans, Gonnie Nodelijk, Elisabeth A. M. Sanders, Joris Yzermans, Debby Bogaert and Dick Heederik

    Pneumonia 2017 9:3

    Published on: 25 February 2017

  10. Review

    Pulmonary infections in the returned traveller

    Pulmonary infections in the returned traveller are a common presentation. A wide variety of infections may present with pulmonary symptoms. It is important for clinicians to differentiate the cause of these sy...

    Ashleigh Trimble, V. Moffat and A. M. Collins

    Pneumonia 2017 9:1

    Published on: 25 January 2017

  11. Review

    Tuberculosis and pneumonia in HIV-infected children: an overview

    Pneumonia remains the most common cause of hospitalization and the most important cause of death in young children. In high human immunodeficiency virus (HIV)-burden settings, HIV-infected children carry a hig...

    Helena Rabie and Pierre Goussard

    Pneumonia 2016 8:19

    Published on: 24 November 2016

  12. Research

    Non-adherence to community oral-antibiotic treatment in children with fast-breathing pneumonia in Malawi– secondary analysis of a prospective cohort study

    Despite significant progress, pneumonia is still the leading cause of infectious deaths in children under five years of age. Poor adherence to antibiotics has been associated with treatment failure in World He...

    Rebecca Nightingale, Tim Colbourn, David Mukanga, Limangeni Mankhambo, Norman Lufesi, Eric D. McCollum and Carina King

    Pneumonia 2016 8:21

    Published on: 24 November 2016

  13. Review

    Global burden of childhood tuberculosis

    In 2015, the World Health Organization (WHO) declared tuberculosis (TB) to be responsible for more deaths than any other single infectious disease. The burden of TB among children has frequently been dismissed...

    Helen E. Jenkins

    Pneumonia 2016 8:24

    Published on: 24 November 2016

  14. Review

    Novel vaccination approaches to prevent tuberculosis in children

    Pediatric tuberculosis (TB) is an underappreciated problem and accounts for 10 % of all TB deaths worldwide. Children are highly susceptible to infection with Mycobacterium tuberculosis and interrupting TB spread...

    James A. Triccas and Claudio Counoupas

    Pneumonia 2016 8:18

    Published on: 24 November 2016

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